TLR4 regulates ROS and autophagy to control neutrophil extracellular traps formation against Streptococcus pneumoniae in acute otitis media
Yilin Dong, Chunfang Jin, Zhiqiang Ding, Yiting Zhu, Qian He, Xinxin Zhang, Rongshuang Ai, Yibing Yin, Yujuan He
Topics & Concepts
AutophagyIn vivoIn vitroNeutrophil extracellular trapsOtitisStreptococcus pneumoniaeReactive oxygen speciesChemistryTLR4ExtracellularCell biologyMicrobiologyBiologyImmunologyApoptosisSignal transductionInflammationBiochemistryAntibioticsGeneticsBiotechnologyNeutrophil, Myeloperoxidase and Oxidative MechanismsEar Surgery and Otitis MediaNeonatal and Maternal Infections