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Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis

Mark P. Roberto, Gabriele Varano, Rosa Viñas-Castells, Antony B. Holmes, Rahul Kumar, Laura Pasqualucci, Pedro Farinha, David W. Scott, David Dominguez-Sola

2021Immunity27 citationsDOIOpen Access PDF

Topics & Concepts

FOXO1BiologyGerminal centerTranscription factorCancer researchB cellKinaseGeneticsGeneAntibodyFOXO transcription factor regulationT-cell and B-cell ImmunologyCAR-T cell therapy research
Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis | Litcius