Brain Tumor: An overview of the basic clinical manifestations and treatment
Abolanle A. A. Kayode, Shahzadi Amina, Muhammad Akram, Anwar Hina, Omowumi T. Kayode, Akinnawo Omowumi O, Olayinka S. Okoh
Abstract
Brain tumor constitutes 2-3% of all malignant neoplasms and nearly 85-90% of all primary CNS tumors, with an estimated fi ve-year survival rate of up to 35% for malignant tumors and about 90% for benign tumors Studies put brain tumors in the list of most common malignancy after leukemia in children with an incidence of up to 25% Growing prevalence rate in developed countries may be attributed to availability of advanced techniques for detection and diagnosis when compared to that of developing countries where most people have limited access to equipment for early detection. This results in undiagnosed and unregistered cases, thereby, decreasing the level of incidence and prevalence reported [4]. Brain tumors are diagnosed at the age of 3-12 years in children and 40 -70 years in adults. Brain tumors range from benign to malignant and eventually to metastatic tumors. Metastatic brain tumors are more prevalent in adults [5]. Carcinomas metastasizing to brain include lung, breast, skin (melanoma), kidney and colon with predominant contribution made by lung cancer (small cell lung cancer), accounting for about one half of all disseminated cases, according to reports from various