Notch1 signaling modulates hypoxia-induced multidrug resistance in human laryngeal cancer cells
Dawei Li, Dan Xu, Penghui Chen, Jin Xie
Topics & Concepts
SurvivinHES1Cancer researchDownregulation and upregulationSmall interfering RNAABCC1Flow cytometryApoptosisMultiple drug resistanceCancer cellBiologyHypoxia (environmental)CancerSignal transductionNotch signaling pathwayChemistryDrug resistanceMolecular biologyCell cultureTransfectionCell biologyGeneATP-binding cassette transporterOxygenBiochemistryGeneticsTransporterOrganic chemistryMicrobiologyCancer, Hypoxia, and MetabolismDrug Transport and Resistance MechanismsDevelopmental Biology and Gene Regulation