A Meroisoprenoid, Heptenolides, and <i>C</i>-Benzylated Flavonoids from <i>Sphaerocoryne gracilis</i> ssp. <i>gracilis</i>
Gasper Maeda, Joan J. E. Munissi, Sofia Lindblad, Sandra Duffy, Jerry Pelletier, Vicky M. Avery, Stephen S. Nyandoro, Máté Erdélyi
Abstract
values of 1.4-10.5 μM, although these compounds also showed cytotoxicity against human embryonic kidney HEK-293 cells. None of the compounds exhibited significant disruption in protein translation when assayed in vitro.
Topics & Concepts
Bark (sound)Plasmodium falciparumCytotoxicityIn vitroChemistryStereochemistryHEK 293 cellsBiologyBotanyBiochemistryGeneMalariaImmunologyEcologyTraditional and Medicinal Uses of AnnonaceaeBioactive natural compoundsMarine Sponges and Natural Products