In the pursuit of novel therapeutic agents: synthesis, anticancer evaluation, and physicochemical insights of novel pyrimidine-based 2-aminobenzothiazole derivatives
Toka I. Ismail, Nashwa El‐Khazragy, Rasha A. Azzam
Abstract
. Furthermore, the computed drug likeness and ADMET properties of the most potent synthesized compounds suggest their potential as promising candidates for further development, with favorable bioavailability and pharmacokinetic profiles.
Topics & Concepts
PyrimidineCombinatorial chemistryChemistryPharmacologyStereochemistryMedicineSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsQuinazolinone synthesis and applications