N-Linked Glycosylation Plays an Important Role in Budding of Neuraminidase Protein and Virulence of Influenza Viruses
Danqi Bao, Ruixue Xue, Min Zhang, Chenyang Lu, Tianxin Ma, Chaochao Ren, Ting Zhang, Jianmei Yang, Qiaoyang Teng, Xuesong Li, Zejun Li, Qinfang Liu
Abstract
NA is a highly glycosylated protein. Nevertheless, how the NLG affects the function of NA protein remains largely unclear.
Topics & Concepts
BiologyVirulenceNeuraminidaseVirologyGlycosylationBuddingH5N1 genetic structureInfluenza A virusGlycoproteinInfluenza A virus subtype H5N1MicrobiologyVirusCell biologyCoronavirus disease 2019 (COVID-19)GeneticsGeneInfectious disease (medical specialty)MedicineDiseasePathologyInfluenza Virus Research StudiesViral gastroenteritis research and epidemiologyinterferon and immune responses