Systems-level effects of allosteric perturbations to a model molecular switch
Tina Perica, Christopher J.P. Mathy, Jiewei Xu, Gwendolyn Μ. Jang, Yang Zhang, Robyn M. Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme
Topics & Concepts
Allosteric regulationComputer scienceBiologyGeneticsReceptorComputational Drug Discovery MethodsProtein Structure and DynamicsAdvanced Fluorescence Microscopy Techniques