A combined screening study for evaluating the potential of exhaled acetone, isoprene, and nitric oxide as biomarkers of lung cancer
Hao Wang, Xin Wei, Yinghua Wu, Bojun Zhang, Qing Chen, Weigui Fu, Meixiu Sun, Hongxiao Li
Abstract
: the model, established with acetone, isoprene, and NO as predictors, possesses the ability to identify LC patients from healthy control (HC) participants. The CRDS instrument, which simultaneously detects acetone, isoprene, and NO, is expected to be a non-invasive, rapid, portable, and accurate device for early screening of LC.
Topics & Concepts
IsopreneExhaled airBreath gas analysisExhalationLung cancerReceiver operating characteristicLogistic regressionChemistryMedicineChromatographyOncologyInternal medicineRadiologyToxicologyOrganic chemistryPolymerBiologyCopolymerAdvanced Chemical Sensor TechnologiesMetabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications