Direct C–H Dehydrogenative Germylation of Terminal Alkynes with Hydrogermanes
Amit Dahiya, Franziska Schoenebeck
Abstract
A direct C(sp)–H germylation of terminal alkynes with triethyl germanium hydride is reported. The method is operationally simple and makes use of B(C6F5)3 catalysis in combination with 2,6-lutidine as an organic base. Exclusive selectivity for dehydrogenative germylation of the alkyne over the competing hydrogermylation is observed.
Topics & Concepts
ChemistryTerminal (telecommunication)AlkyneSelectivityHydrideCatalysisCombinatorial chemistryBase (topology)Medicinal chemistryStereochemistryOrganic chemistryHydrogenComputer scienceComputer networkMathematical analysisMathematicsCatalytic C–H Functionalization MethodsOrganoboron and organosilicon chemistryCatalytic Cross-Coupling Reactions