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<i>In silico</i> screening of phytopolyphenolics for the identification of bioactive compounds as novel protease inhibitors effective against SARS-CoV-2

Mithun Rudrapal, Abdul Rashid Issahaku, Clement Agoni, Atul R. Bendale, Akhil Nagar, Mahmoud E. S. Soliman, Deepak K. Lokwani

2021Journal of Biomolecular Structure and Dynamics81 citationsDOI

Abstract

techniques to assess their potential efficacy against SARS-CoV-2 and thus serve as the starting point for the development of potent antiviral agents against the deadly COVID-19.

Topics & Concepts

ProteasesMyricetinProteaseVirtual screeningChemistryDocking (animal)In silicoBiochemistryTaxifolinPolyphenolNaringeninDrug discoveryEnzymeKaempferolFlavonoidAntioxidantGeneNursingMedicineComputational Drug Discovery MethodsDiverse Scientific Research StudiesMedicinal Plant Research
<i>In silico</i> screening of phytopolyphenolics for the identification of bioactive compounds as novel protease inhibitors effective against SARS-CoV-2 | Litcius