Near-Infrared Fluorescent Probe Activated by Nitroreductase for <i>In Vitro</i> and <i>In Vivo</i> Hypoxic Tumor Detection
Sanu Karan, Mi Young Cho, Hyun-Seung Lee, Hwunjae Lee, Hye Sun Park, Mahesh Sundararajan, Jonathan L. Sessler, Kwan Soo Hong
Abstract
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Topics & Concepts
NitroreductaseIn vivoChemistryBODIPYIn vitroFluorescenceFlow cytometryHypoxia (environmental)Cancer cellTumor hypoxiaBiophysicsConfocalCancer researchCancerMolecular biologyBiochemistryBiologyEnzymeMedicineOxygenInternal medicineQuantum mechanicsGeometryBiotechnologyOrganic chemistryRadiation therapyGeneticsMathematicsPhysicsNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismPhotodynamic Therapy Research Studies