MRI of focal cortical dysplasia
Horst Urbach, Elias Kellner, Nico Kremers, Ingmar Blümcke, Theo Demerath
Abstract
Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet. Only FCD type II have distinctive MRI and molecular genetics alterations so far. Subtle FCD including FCD type II located in the depth of a sulcus are often overlooked requiring the use of dedicated sequences (MP2RAGE, FLAWS, EDGE) and/or voxel (VBM)- or surface-based (SBM) postprocessing. The added value of 7 Tesla MRI has to be proven yet.
Topics & Concepts
Cortical dysplasiaNeuroradiologyMedicinePathologyDysplasiaMagnetic resonance imagingVoxelNeurologyAnatomyRadiologyPsychiatryGlioma Diagnosis and TreatmentAdvanced MRI Techniques and ApplicationsEpilepsy research and treatment