Various Mobile Genetic Elements Involved in the Dissemination of the Phenicol-Oxazolidinone Resistance Gene <i>optrA</i> in the Zoonotic Pathogen Streptococcus suis: a Nonignorable Risk to Public Health
Xingyang Dai, Junjie Sun, Boqin Zhu, Mingsiyi Lv, Liye Chen, Li Chen, Xiaoming Wang, Jinhu Huang, Liping Wang
Abstract
Antimicrobial resistance to phenicols and oxazolidinones by the dissemination of the optrA gene leads to treatment failure in both veterinary and human medicine. However, information about the profile of these MGEs (mobilome) that carry optrA and their transferability in streptococci was limited, especially for the zoonotic pathogen S. suis .
Topics & Concepts
Mobile genetic elementsProphageGeneticsBiologyPlasmidHorizontal gene transferStreptococcus suisGeneGenomeMicrobiologyVirulenceBacteriophageEscherichia coliStreptococcal Infections and TreatmentsAntimicrobial Resistance in StaphylococcusPlant Pathogenic Bacteria Studies