Transmetalation of boronic acids and their derivatives: mechanistic elucidation and relevance to catalysis
Kohtaro Osakada, Yasushi Nishihara
Abstract
on the pathways of the catalytic Suzuki-Miyaura reaction. The reactions of arylboronic acids with Rh(I)-OH complexes were investigated, which are relevant to the mechanism of Rh-catalysed addition of aryl boronic acids to enones and aldehydes. Recent studies on the transmetalation of boronic acids with other late transition metals such as Fe(II), Co(I), Pt(II), Au(III), and Au(I) are presented with the related catalytic reactions and their utilisation in the synthesis of aromatic molecules and π-conjugated materials.
Topics & Concepts
TransmetalationChemistryBoronic acidCatalysisCatalytic cycleArylOrganic chemistryCombinatorial chemistryAryl halideOrganic synthesisReaction mechanismReductive eliminationMedicinal chemistryPalladiumAlkylCatalytic Cross-Coupling ReactionsCoordination Chemistry and OrganometallicsOrganoboron and organosilicon chemistry