Diversity and Long-Term Dynamics of Human Blood Anelloviruses
Joanna Kaczorowska, Martin Deijs, Michelle Klein, Margreet Bakker, Maarten F. Jebbink, Mila Sparreboom, Cormac M. Kinsella, Anne L. Timmerman, Lia van der Hoek
Abstract
Knowledge of the persistence of AVs in humans is crucial to our understanding of the nature of AV infection (chronic or acute) and the role of AV in the host. We therefore investigated the dynamics of anellovirus infection in two healthy people followed up for 30 years. Our findings suggest that the human blood anellovirus virome (anellome) remains stable and personal for decades.
Topics & Concepts
Torque teno virusHuman viromeBiologyPopulationPersistence (discontinuity)MicrobiomeHost (biology)Human bloodZoologyEvolutionary biologyGeneticsGenotypePhysiologyMetagenomicsGeneDemographyEngineeringGeotechnical engineeringSociologyAnimal Virus Infections StudiesVirus-based gene therapy researchPlant Virus Research Studies