Specific Knockdown of α-Synuclein by Peptide-Directed Proteasome Degradation Rescued Its Associated Neurotoxicity
Jing Qu, Xiaoxi Ren, Fenqin Xue, Yi He, Ruihua Zhang, Yan Zheng, Haixia Huang, Wei Wang, Jianliang Zhang
Topics & Concepts
Gene knockdownNeurotoxicityDegradation (telecommunications)ProteasomePeptideCell biologyChemistryBiochemistryBiologyComputer scienceToxicityGeneTelecommunicationsOrganic chemistryParkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathwaysAlzheimer's disease research and treatments