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Elevated trophoblastic Siglec6 contributes to the impairment of vascular endothelial cell functions by downregulating Wnt6/β-catenin signaling in preeclampsia

Xiaonian Guan, Ming Yu, Linlin Wu, Jie Chen, Jianing Tong, Xiaoxia Wu, Aiqi Yin, Tianxia Xiao, Baobei Wang, Jian V. Zhang, Jianmin Niu

2022Archives of Biochemistry and Biophysics13 citationsDOI

Topics & Concepts

SyncytiotrophoblastsDownregulation and upregulationWnt signaling pathwayBiologyUmbilical veinSignal transductionCancer researchCell biologyEndothelial stem cellPlacentationCell growthPlacentaStromal cellImmunologyIn vitroFetusGenePregnancyGeneticsPregnancy and preeclampsia studiesNeonatal Respiratory Health ResearchCongenital Diaphragmatic Hernia Studies
Elevated trophoblastic Siglec6 contributes to the impairment of vascular endothelial cell functions by downregulating Wnt6/β-catenin signaling in preeclampsia | Litcius