Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas
Shivem B. Shah, Christopher R. Carlson, Kristine Lai, Zhe Zhong, Grazia Marsico, Katherine M. Lee, Nicole E. Félix Vélez, Elisabeth B. Abeles, Mayar Allam, Thomas Hu, Lauren D. Walter, Karen E. Martin, Khanjan Gandhi, Scott D. Butler, Rishi Puri, Angela L. McCleary‐Wheeler, Wayne Tam, Olivier Elemento, Katsuyoshi Takata, Christian Steidl, David W. Scott, Lorena Fontán, Hideki Ueno, Benjamin D. Cosgrove, Giorgio Inghirami, Andrés J. Garcı́a, Ahmet F. Coskun, Jean L. Koff, Ari Melnick, Ankur Singh
Topics & Concepts
Cancer researchTumor microenvironmentBruton's tyrosine kinasebreakpoint cluster regionBiologyLymphomaB-cell receptorDiffuse large B-cell lymphomaB cellSignal transductionImmunologyTyrosine kinaseCell biologyReceptorAntibodyTumor cellsBiochemistryImmune Cell Function and InteractionLymphoma Diagnosis and TreatmentCancer Immunotherapy and Biomarkers