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BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells

Chen Yao, Guohua Lou, Hong‐Wei Sun, Ziang Zhu, Yi Sun, Zeyu Chen, Daniel Chauss, E. Ashley Moseman, Jun Cheng, Marc D’Antonio, Wangke Shi, Junwei Shi, Kohei Kometani, Tomohiro Kurosaki, E. John Wherry, Behdad Afzali, Luca Gattinoni, Yuwen Zhu, Dorian B. McGavern, John J. O’Shea, Pamela L. Schwartzberg, Tuoqi Wu

2021Nature Immunology200 citationsDOIOpen Access PDF

Topics & Concepts

BiologyStem cellCD8Cytotoxic T cellEpigeneticsCell biologyEpigenomicsCellular differentiationCancer researchImmunologyGeneticsGeneGene expressionImmune systemDNA methylationIn vitroCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses
BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells | Litcius