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The current status of biotechnological production and the application of a novel antioxidant ergothioneine

Yiwen Han, Xiuyang Tang, Yuting Zhang, Xuechao Hu, Lujing Ren

2021Critical Reviews in Biotechnology62 citationsDOI

Abstract

Ergothioneine is a sulfur-containing histidine derivative, that possessesexcellent antioxidant activity and has been used in the food and cosmetics industries. It plays a significant role in anti-aging and the prevention of various diseases. This review will briefly introduce the functions and applications of ergothioneine, elaborate the biosynthetic pathways of ergothioneine and describe several strategies to increase the production of ergothioneine. Then the efficient extraction and detection methods of ergothioneine will be presented. Finally, several proposals are put forward to increase the yield of ergothioneine, and the development prospects of ergothioneine will be discussed.

Topics & Concepts

ErgothioneineAntioxidantChemistryYield (engineering)BiochemistryBiotechnologyBiologyMaterials scienceMetallurgyFungal Biology and ApplicationsPharmacological Effects of Natural CompoundsMedicinal Plants and Bioactive Compounds
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