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ATP13A2 deficiency disrupts lysosomal polyamine export

Sarah van Veen, Shaun Martin, Chris Van den Haute, Veronick Benoy, Joseph A. Lyons, Roeland Vanhoutte, Jan Kähler, Jean-Paul Decuypere, Géraldine Gelders, Eric J. Lambie, Jeffrey Zielich, Johannes V. Swinnen, Wim Annaert, Patrizia Agostinis, Bart Ghesquière, Steven H. L. Verhelst, Veerle Baekelandt, Jan Eggermont, Peter Vangheluwe

2020Nature327 citationsDOIOpen Access PDF

Topics & Concepts

NeurodegenerationPolyamineLysosomeCell biologySpermineBiologyLysosomal storage diseaseAutophagyBiochemistryInternal medicineDiseaseApoptosisMedicineEnzymeAutophagy in Disease and TherapyPolyamine Metabolism and ApplicationsParkinson's Disease Mechanisms and Treatments
ATP13A2 deficiency disrupts lysosomal polyamine export | Litcius