Litcius/Paper detail

Cell-type-specific population dynamics of diverse reward computations

Emily Sylwestrak, YoungJu Jo, Sam Vesuna, Xiao Wang, Blake Holcomb, Rebecca H. Tien, Doo Kyung Kim, Lief E. Fenno, Charu Ramakrishnan, William E. Allen, Ritchie Chen, Krishna V. Shenoy, David Sussillo, Karl Deisseroth

2022Cell80 citationsDOIOpen Access PDF

Abstract

cells might integrate reward history, which was complemented by in vivo experimentation. This integrated approach describes a process by which data-driven computational models of population activity can generate and frame actionable hypotheses for cell-type-specific investigation in biological systems.

Topics & Concepts

BiologyPopulationDynamics (music)Type (biology)Computational biologyEcologyAcousticsSociologyDemographyPhysicsNeural dynamics and brain functionGene Regulatory Network AnalysisReceptor Mechanisms and Signaling