The expanding family of T follicular regulatory cells
Luís Graça, Johanne T. Jacobsen, Saumya Kumar
Abstract
The coevolution of multiple specialized T follicular regulatory cell subsets has led to fine-tuning of human germinal center responses in providing optimal antibody production and preventing events leading to autoimmunity (see the related Research Article by Le Coz et al .).
Topics & Concepts
Germinal centerFollicular phaseAutoimmunityCoevolutionBiologyImmunologyCell biologyAntibodyB cellGeneticsEvolutionary biologyImmune Cell Function and InteractionT-cell and B-cell ImmunologyDiabetes and associated disorders