Therapeutic drug monitoring of tranexamic acid in plasma and urine of renally impaired patients using solid phase microextraction
Nikita Looby, Tijana Vasiljević, Nathaly Reyes‐Garcés, Anna Roszkowska, Barbara Bojko, Marcin Wąsowicz, Angela Jerath, Janusz Pawliszyn
Topics & Concepts
ChemistryChromatographyTranexamic acidUrineTherapeutic drug monitoringDosingSolid-phase microextractionDerivatizationPharmacokineticsDetection limitSample preparationPharmacologyHigh-performance liquid chromatographyGas chromatography–mass spectrometryMass spectrometrySurgeryMedicineBlood lossBiochemistryOrganic chemistryBlood transfusion and managementForensic Toxicology and Drug AnalysisAntibiotics Pharmacokinetics and Efficacy