Litcius/Paper detail

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus

Sriram Vaidyanathan, Ron Baik, Lü Chen, Dawn T. Bravo, Carlos J. Suarez, Shayda M. Abazari, Ameen A. Salahudeen, Amanda M. Dudek, Christopher A. Teran, Timothy Davis, Ciaran M. Lee, Gang Bao, Scott H. Randell, Steven E. Artandi, Jeffrey J. Wine, Calvin J. Kuo, Tushar Desai, Jayakar V. Nayak, Zachary M. Sellers, Matthew H. Porteus

2021Molecular Therapy69 citationsDOIOpen Access PDF

Topics & Concepts

Cystic fibrosis transmembrane conductance regulatorCystic fibrosisBiologyCRISPRGenetic enhancementMutationStem cellMolecular biologyGeneticsGeneImmunologyCystic Fibrosis Research AdvancesEnergy Harvesting in Wireless NetworksCRISPR and Genetic Engineering