C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly
Tao Wang, Honghe Liu, Kie Itoh, Sungtaek Oh, Liang Zhao, Daisuke Murata, Hiromi Sesaki, Thomas Härtung, Chan Hyun Na, Jiou Wang
Topics & Concepts
C9orf72Cell biologyMitochondrionBiologyNeurodegenerationIntermembrane spaceAmyotrophic lateral sclerosisHaploinsufficiencyProteostasisCardiolipinBiochemistryBacterial outer membraneTrinucleotide repeat expansionPhenotypePhospholipidMedicineMembranePathologyEscherichia coliAlleleGeneDiseaseMitochondrial Function and PathologyAmyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments