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BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development

Lia Heinemann‐Yerushalmi, Lital Bentovim, Neta Felsenthal, Ron Carmel Vinestock, Nofar Michaeli, Sharon Krief, Alon Silberman, Marina Cohen, Shifra Ben‐Dor, Ori Brenner, Rebecca Haffner‐Krausz, Maxim Itkin, Sergey Malitsky, Ayelet Erez, Elazar Zelzer

2021Developmental Cell27 citationsDOIOpen Access PDF

Topics & Concepts

BiologyPyruvate dehydrogenase complexPDK4Citric acid cycleCatabolismKinasePhosphorylationCrosstalkCell biologyEmbryonic stem cellBiochemistryGeneMetabolismEnzymePhysicsOpticsPancreatic function and diabetesEpigenetics and DNA MethylationCancer, Hypoxia, and Metabolism
BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development | Litcius