Phenotypic and Genomic Comparison of Staphylococcus aureus Highlight Virulence and Host Adaptation Favoring the Success of Epidemic Clones
Fengning Chen, Yuyao Yin, Hongbin Chen, Longyang Jin, Shuguang Li, Ruobing Wang, Shuyi Wang, Qi Wang, Shijun Sun, Hui Wang
Abstract
= 983) accompanied by a rigorous strain selection process. A combination of host cell-pathogen interactions and genomic analyses was applied to the represented strains. We revealed some potential genomic traits associated with virulence and fitness that might account for the success of epidemic clones.
Topics & Concepts
VirulenceStaphylococcus aureusBiologyMicrobiologyGenePhenotypePathogenHost adaptationGeneticsBacteriaAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingBiochemical and Structural Characterization