The impact of genetic variants related to vitamin D and autoimmunity: A systematic review
Luisa Menezes Trefilio, Letícia Bottino, Rafaella de Carvalho Cardoso, Guilherme Carneiro Montes, Fabrícia Lima Fontes-Dantas
Abstract
gene]. Therefore, our findings confirmed the associations of several genetic variants of vitamin D signaling with a broad spectrum of autoimmune diseases/traits. In addition, given the low number of papers found with functional analysis, further studies to elucidate the real effect that the variants exert on Vitamin D signaling are recommended.
Topics & Concepts
FokITaqICalcitriol receptorVitamin D and neurologyAutoimmunityGeneticsBiologyGeneVitamin D-binding proteinImmunologyNuclear receptorAlleleEndocrinologyTranscription factorAntibodyPolymorphism (computer science)Vitamin D Research StudiesAdrenal Hormones and DisordersDiabetes and associated disorders