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Senescent cells as thermostats of antitumor immunity

Luis I. Prieto, Ines Sturmlechner, Jörg J. Goronzy, Darren J. Baker

2023Science Translational Medicine21 citationsDOIOpen Access PDF

Abstract

Harnessing the immunogenic potential of senescent cells may be a viable but context-dependent opportunity to boost antitumor immunity.

Topics & Concepts

ImmunityContext (archaeology)ThermostatImmunologyBiologyImmune systemMedicineCell biologyEngineeringPaleontologyMechanical engineeringTelomeres, Telomerase, and SenescenceImmunotherapy and Immune ResponsesCytomegalovirus and herpesvirus research
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