Electrochemical Trifluoromethylation of Thiophenols with Sodium Trifluoromethanesulfinate
Xingxing Zhu, Huai-Qin Wang, Chenguang Li, Xiaolan Xu, Jun Xu, Jianjun Dai, Hua‐Jian Xu
Abstract
We developed an electrochemical trifluoromethylation of thiophenols without the use of metal catalysts and oxidants. This reaction features mild reaction conditions, readily available substrate, as well as moderate to good yields. In addition, this protocol can be easily scaled up with moderate efficiency.
Topics & Concepts
TrifluoromethylationChemistryElectrochemistryCatalysisSubstrate (aquarium)MetalSodiumReaction conditionsCombinatorial chemistryInorganic chemistryOrganic chemistryElectrodePhysical chemistryTrifluoromethylGeologyAlkylOceanographyFluorine in Organic ChemistrySulfur-Based Synthesis TechniquesRadical Photochemical Reactions