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Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics

Vadim Fedyuk, Nir Erez, Noa Furth, Olga Beresh, Ekaterina N. Andreishcheva, Abhijeet Shinde, Daniel Jones, Barak Bar Zakai, Yael Mavor, Tamar Peretz, Ayala Hubert, Jonathan Cohen, Azzam Salah, Mark Temper, Albert Grinshpun, Myriam Maoz, Aviad Zick, G. Ron, Efrat Shema

2022Nature Biotechnology89 citationsDOI

Topics & Concepts

EpigeneticsHistoneColorectal cancerCancerDNA methylationPancreatic cancerNucleosomeLiquid biopsyBiologyCancer researchDNACell-free fetal DNAChemistryComputational biologyBiochemistryGeneticsGeneGene expressionFetusPregnancyPrenatal diagnosisCancer Genomics and DiagnosticsEpigenetics and DNA MethylationSingle-cell and spatial transcriptomics
Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics | Litcius