Endocrinal dysfunction in children with Down syndrome
Kotb Abbass Metwalley, Hekma Saad Farghaly
Abstract
Down syndrome (DS) is the most common genetic disorder in live-born infants. Children with DS are at increased risk of numerous endocrinal comorbidities. The information contained in this article will provide pediatricians with a narrative overview of different presentations, diagnoses, and management recommendations of various endocrinal disorders in children with DS. We systematically searched PubMed, Embase, Google Scholar, MEDLINE, EBSCO, and Science Direct, and potentially relevant articles were identified and retrieved from electronic and print journals.
Topics & Concepts
MedicineMEDLINENarrative reviewPediatricsMedical diagnosisDown syndromeFamily medicineIntensive care medicinePsychiatryPathologyLawPolitical scienceDown syndrome and intellectual disability researchHyperglycemia and glycemic control in critically ill and hospitalized patientsNeonatal Respiratory Health Research