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Mechanistic prediction of first-in-human dose for bispecific CD3/EpCAM T-cell engager antibody M701, using an integrated PK/PD modeling method

Ling Song, Junsheng Xue, Jing Zhang, Si Li, Dongyang Liu, Tianyan Zhou

2020European Journal of Pharmaceutical Sciences20 citationsDOI

Topics & Concepts

Bispecific antibodyT cellAntibodyChemistryCD3Cancer researchBiologyAntigenImmune systemImmunologyMonoclonal antibodyCD8Monoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy researchHER2/EGFR in Cancer Research
Mechanistic prediction of first-in-human dose for bispecific CD3/EpCAM T-cell engager antibody M701, using an integrated PK/PD modeling method | Litcius