Relationship between activity and stability: Design and characterization of stable variants of human frataxin
Ignacio Hugo Castro, Mauro Bringas, Davide Doni, Martín E. Noguera, Luciana Capece, Martı́n Arán, Matı́as Blaustein, Paola Costantini, Javier Santos
Topics & Concepts
FrataxinMitochondrial matrixProteolysisChemistryBiophysicsProtein structureFunction (biology)Protein subunitBiologyCrystallographyBiochemistryIron-binding proteinsGeneticsGeneEnzymeCytosolGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyFungal and yeast genetics research