Real-time imaging of cell-surface proteins with antibody-based fluorogenic probes
Wenchao Wang, Ying Zhang, Hong Zhao, Xinlei Zhuang, Haoting Wang, Kaifeng He, Wanting Xu, Yu Kang, Shuqing Chen, Su Zeng, Linghui Qian
Abstract
a two-step chemical modification under physiological conditions, to fulfill the selective recognition and wash-free imaging of membrane proteins, establishing a modular strategy with broad implications for biochemical research and for therapeutics.
Topics & Concepts
AntibodyChemistryCellBiophysicsComputational biologyBiochemistryBiologyImmunologyMonoclonal and Polyclonal Antibodies ResearchAdvanced Biosensing Techniques and ApplicationsClick Chemistry and Applications