Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling
Shuya Kate Huang, Aditya Pandey, Duy Phuoc Tran, Nicolas Villanueva, Akio Kitao, Roger K. Sunahara, Adnan Sljoka, R. Scott Prosser
Topics & Concepts
Heterotrimeric G proteinG protein-coupled receptorAllosteric regulationBiologyG proteinAdenosine A2A receptorBiophysicsStructural biologyNuclear magnetic resonance spectroscopyBiochemistryAdenosine receptorSignal transductionAgonistReceptorStereochemistryChemistryReceptor Mechanisms and SignalingAdenosine and Purinergic SignalingNeuropeptides and Animal Physiology