Lnc-HZ08 regulates BPDE-induced trophoblast cell dysfunctions by promoting PI3K ubiquitin degradation and is associated with miscarriage
Jiayu Xie, Tingting Liang, Jingsong Zhao, Zhongyan Xu, Peng Tian, Rong Wang, Chenyang Mi, Wenxin Huang, Weina Chen, Huidong Zhang
Topics & Concepts
TrophoblastPI3K/AKT/mTOR pathwayUbiquitin ligaseDNA methylationBiologyProtein kinase BMethylationCell biologyUbiquitinChemistryCancer researchSignal transductionPlacentaBiochemistryGene expressionFetusGeneticsDNAPregnancyGeneCancer-related molecular mechanisms researchCircular RNAs in diseasesRNA modifications and cancer