Anti‐inflammatory and immune‐mediated therapy for a case of febrile infection‐related epilepsy syndrome with rapid recurrence
Tomonori Kurimoto, Tsuyoshi Matsuoka, Yuki Ami, Koji Kanno, Takashi Fujii, Naoki Fujiwara, Takashi Matsuoka
Abstract
Febrile infection-related epilepsy syndrome (FIRES) is a disease of unknown etiology, characterized by refractory frequent focal seizures, which require prolonged intensive care. We successfully treated a boy with FIRES with anti-inflammatory and immunosuppressive therapy. This case suggests that an autoimmune mechanism may play a role in the development of FIRES.
Topics & Concepts
MedicineEtiologyEpilepsyRefractory (planetary science)DiseaseImmune systemEpilepsy syndromesIntensive care medicineImmunologyPediatricsInternal medicinePsychiatryPhysicsAstrobiologyInfectious Encephalopathies and EncephalitisEpilepsy research and treatmentBacterial Infections and Vaccines