Incidence of diabetes mellitus in Spain as results of the nation-wide cohort [email protected] study
Gemma Rojo‐Martínez, Sergio Valdés, Federico Soriguer, Joan Vendrell, Inés Urrutia, Vidal Pérez, E. Ortega, P. Ocón, Eduard Montanya, Edelmiro Menéndez Torre, Ana Lago‐Sampedro, T. González- Frutos, Ramón Gomis, Albert Goday, Sara García‐Serrano, Eva García‐Escobar, José Luis Galán–García, Conxa Castell, Rocío Badía-Guillén, Gabriel Aguilera‐Venegas, J. Girbés, Sonia Gaztambide, Josep Franch‐Nadal, Elías Delgado, Felipe Javier Chaves, Luís Castaño, Alfonso L. Calle‐Pascual
Abstract
Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain ([email protected] study). The target was the Spanish population. In total 5072 people older than 18 years,were randomly selected from all over Spain). Socio-demographic and clinical data, survey on habits (physical activity and food consumption) and weight, height, waist, hip and blood pressure were recorder. A fasting blood draw and an oral glucose tolerance test were performed. Determinations of serum glucose were made. In the follow-up the same variables were collected and HbA1c was determined. A total of 2408 subjects participated in the follow-up. In total, 154 people developed diabetes (6.4% cumulative incidence in 7.5 years of follow-up). The incidence of diabetes adjusted for the structure of age and sex of the Spanish population was 11.6 cases/1000 person-years (IC95% = 11.1-12.1). The incidence of known diabetes was 3.7 cases/1000 person-years (IC95% = 2.8-4.6). The main risk factors for developing diabetes were the presence of prediabetes in cross-sectional study, age, male sex, obesity, central obesity, increase in weight, and family history of diabetes. This work provides data about population-based incidence rates of diabetes and associated risk factors in a nation-wide cohort of Spanish population.