Methylation-dependent and -independent roles of EZH2 synergize in CDCA8 activation in prostate cancer
Yi Yang, Yanqiang Li, Chao Li, Longxiang Wu, Dongyu Zhao, Fuxi Li, Ladan Fazli, Rui Wang, Long Wang, Xuesen Dong, Wei Zhao, Kaifu Chen, Qi Cao
Topics & Concepts
EZH2BiologyCancer researchMethyltransferaseMethylationE2F1PRC2Transcription factorDNA methylationProstate cancerEnhancerCell cycleTranscription (linguistics)CancerGeneticsGene expressionGeneLinguisticsPhilosophyEpigenetics and DNA MethylationProstate Cancer Treatment and ResearchUbiquitin and proteasome pathways