Determination of pKa values and deprotonation order of methotrexate using a combined experimental-theoretical study and binding constants of the methotrexate-Laponite complex at different pH values
J.C. Alva-Ensastegui, Enrique Morales-Ávila, Alexander Pérez de la Luz, María Josefa Bernad‐Bernad
Topics & Concepts
DeprotonationChemistryAbsorbanceProtonationStability constants of complexesAnalytical Chemistry (journal)StereochemistryPhysical chemistryComputational chemistryChromatographyOrganic chemistryAqueous solutionIonFree Radicals and AntioxidantsChemistry and Chemical EngineeringChemical and Physical Properties in Aqueous Solutions