Silylation of 2<i>H</i>-indazoles by photoinduced hydrogen atom transfer catalysis
Krishna Kanta Das, Alakananda Hajra
Abstract
-indazoles with triphenylsilane has been developed employing 4CzIPN as a photocatalyst and triisopropylsilanethiol as a hydrogen atom transfer (HAT) reagent under aerobic reaction conditions. This method shows tolerance toward many functional groups and affords a variety of silylated indazoles at up to 89% yield. The experimental results suggest that the reaction progresses through a radical pathway.
Topics & Concepts
SilylationCatalysisHydrogen atomPhotochemistryChemistryAtom (system on chip)MetalOrganic chemistryGroup (periodic table)Computer scienceEmbedded systemRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques