Design of a selective and water-soluble fluorescent probe targeting Tau fibrils for intracellular and in vivo imaging
Liang Ji, Xinguang Zhou, Runduo Liu, Liming Wang, Yuanyuan Hu, Jinyu Gu, Zhe Li, Chenglin Li, Tonghui Huang, Yanyan Yu
Topics & Concepts
FluorescenceIn vivoChemistryBiophysicsStokes shiftTriphenylamineFluorescence-lifetime imaging microscopyIn vitroIntracellularConjugated systemPreclinical imagingBiochemistryPhotochemistryPolymerBiologyOrganic chemistryQuantum mechanicsPhysicsBiotechnologyAlzheimer's disease research and treatmentsMolecular Sensors and Ion DetectionNeuroscience and Neuropharmacology Research