Diruthenium(<scp>ii</scp>,<scp>iii</scp>) paddlewheel complexes: effects of bridging and axial ligands on anticancer properties
Iogann Tolbatov, Elisabetta Barresi, Sabrina Taliani, Diego La Mendola, Tiziano Marzo, Alessandro Marrone
Abstract
Diruthenium( ii , iii ) paddlewheel carboxylates combine the pharmacological properties of the dimetallic center with those ascribed to the μ-bridged carboxylates, thus leading to novel, dual-acting anticancer metallodrugs.
Topics & Concepts
ChemistryStereochemistryBridging (networking)Combinatorial chemistryComputer scienceComputer networkMetal complexes synthesis and propertiesOrganometallic Complex Synthesis and CatalysisFerrocene Chemistry and Applications