Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway
Liang Chen, Xiang Shi, Jun Xie, Sheji Weng, Zhong-Jie Xie, Jiahao Tang, Deyi Yan, Bingzhang Wang, Kang-Hao Fang, Chenxuan Hong, Zongyi Wu, Lei Yang
Topics & Concepts
MitophagyAMPKMesenchymal stem cellEndocrinologyOsteoporosisInternal medicineCell biologyApelinOxidative stressBone marrowChemistryMedicineBiologyProtein kinase APhosphorylationAutophagyBiochemistryReceptorApoptosisApelin-related biomedical researchNuclear Receptors and SignalingMacrophage Migration Inhibitory Factor