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AI's role in revolutionizing personalized medicine by reshaping pharmacogenomics and drug therapy

Hamed Taherdoost, Alireza Ghofrani

2024Intelligent Pharmacy100 citationsDOIOpen Access PDF

Abstract

This paper examines the transformative impact of artificial intelligence (AI) on pharmacogenomics, signaling a paradigm shift in personalized medicine. With a focus on enhancing drug response prediction and treatment optimization, AI, particularly machine learning and deep learning algorithms, navigates the complexity of genomic data. By elucidating intricate relationships between genetic factors and drug responses, AI augments the identification of genetic markers and contributes to the development of comprehensive models. The review emphasizes AI's role in guiding treatment decisions, minimizing adverse reactions, and optimizing drug dosages in clinical settings. Ethical considerations, challenges, and future directions are also discussed. This work underscores the synergy of AI and pharmacogenomics, offering a more effective and patient-centric approach to drug therapy, marking a significant advancement in the field of personalized medicine.

Topics & Concepts

PharmacogenomicsPersonalized medicineDrugMedicinePrecision medicinePharmacotherapyPharmacologyBioinformaticsInternal medicineBiologyPathologyComputational Drug Discovery MethodsGenetics, Bioinformatics, and Biomedical ResearchCancer Genomics and Diagnostics
AI's role in revolutionizing personalized medicine by reshaping pharmacogenomics and drug therapy | Litcius