Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria
Clarisse Leseigneur, Pierre Lê-Bury, Javier Pizarro‐Cerdá, Olivier Dussurget
Abstract
Macrophages participate to the first line of defense against infectious agents. Microbial pathogens have evolved sophisticated mechanisms to escape macrophage killing. Here, we review recent discoveries on bacterial molecular strategies to subvert macrophagic immune reponses. We focus on Listeria monocytogenes, Staphylococcus aureus and Yersinia pestis to illustrate the diversity of mechanisms used by microorganisms with different pathogenic lifestyles.
Topics & Concepts
Listeria monocytogenesYersinia pestisBiologyMicrobiologyYersiniaEvasion (ethics)MacrophagePathogenic bacteriaImmune systemYersinia enterocoliticaBacteriaStaphylococcus aureusImmunologyVirulenceGeneticsGeneIn vitroVibrio bacteria research studiesListeria monocytogenes in Food SafetyBacterial biofilms and quorum sensing