The anti-melanogenic effects of ellagic acid through induction of autophagy in melanocytes and suppression of UVA-activated α-MSH pathways via Nrf2 activation in keratinocytes
Hsin‐Ling Yang, Chia-Pei Lin, Yugandhar Vudhya Gowrisankar, Pei‐Jane Huang, Wan-Lin Chang, Sirjana Shrestha, You‐Cheng Hseu
Topics & Concepts
HaCaTMicrophthalmia-associated transcription factorChemistryProtein kinase BDownregulation and upregulationCell biologyPI3K/AKT/mTOR pathwayAutophagyKeratinocyteMAPK/ERK pathwaySignal transductionTyrosinaseBiologyBiochemistryApoptosisIn vitroEnzymeGenemelanin and skin pigmentationSkin Protection and AgingPhytochemicals and Antioxidant Activities